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  • Niclosamide

    19 août 2022

    Niclosamide is being studied in a number of types of cancer. [14] Niclosamide along with oxyclozanide, another anti-tapeworm drug, was found in a 2015 study to display "strong in vivo and in vitro activity against methicillin-resistant Staphylococcus...

  • FISETIN

    19 août 2022

    Fisetin (7,3′,4′-flavon-3-ol) is a plant flavonol from the flavonoid group of polyphenols.[1] It can be found in many plants, where it serves as a yellow/ochre colouring agent. It is also found in many fruits and vegetables, such as strawberries, apples,...

  • Wogonin

    01 septembre 2022

    Wogonin is an O-methylated flavone, a flavonoid-like chemical compound which is found in Scutellaria baicalensis. The glycosides of wogonin are known as wogonosides. For example, oroxindin is a wogonin glucuronide isolated from Oroxylum indicum.[3] It...

  • Los siete principios

    04 septembre 2022

    Los siete principios herméticos "Los principios de la verdad son siete; el que comprenda esto perfectamente, posee la clave mágica ante la cual todas las puertas del Templo se abrirán de par en par". (El Kybalion) Los siete principios sobre los cuales...

  • RESET OF THE HUMAN BEING

    06 novembre 2022

    The reset in the human being is done with fasting for different hours, supplements and eliminating alcohol, fats and cigarettes. Within the different fasts and depending on the hours of fasting, the reset begins by mobilizing fats, eliminating toxins,...

  • Un genio que se vive en la actualidad

    18 décembre 2019

    Fuerzas políticas, socialismo, comunismo Perón y las fuerzas políticas

  • Restauración de la circulación cerebral y las funciones celulares horas post-morten

    26 décembre 2019

    MENU Nature Login Article Published: 17 April 2019 Restoration of brain circulation and cellular functions hours post-morten Zvonimir Vrselja, Stefano G. Daniele, […]Nenad Sestan Nature volume 568, pages336–343(2019)Cite this article 76k Accesses 29...

  • genes involucrados en patologias XII

    24 novembre 2009

    Enfermedades Músculo-esqueléticas ACONDROPLASIA Mutaciones G1138A , G1138C y G375C del gen FGFR3 Secuenciación completa del gen FGFR3 ACONDROGÉNESIS TIPO 1B Secuenciación completa del gen SLC26A2 ACONDROGÉNESIS TIPO 2 Secuenciación completa del gen COL2A1...

  • Rejuvenecimiento, parte II

    06 octobre 2016

    TGF-beta Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 22q13.1 Ensembl cytogenetic band: 22q13.1 HGNC cytogenetic band: 22q13.1 TAB1 Gene in genomic location: bands according to Ensembl, locations...

  • Rejuvenecimiento part III

    06 octobre 2016

    FGF: Factor de crecimiento de fibroblastos (FGF, por fibroblast growth factor) es un factor de crecimiento que aumenta el índice de actividad mitótica y síntesis de ADN facilitando la proliferación de varias células precursoras, como el condroblasto,...

  • Rejuvenecimiento part IV

    06 octobre 2016

    IGF -1: El factor de crecimiento insulínico tipo 1 (también conocido como insulin-like growth factor-1 o IGF-1) es un polipéptido de 70 aminoácidos cuyo peso molecular es de 7650 daltons, que forma parte de un grupo de factores de crecimiento parecidos...

  • Rejuvenecimiento part V

    06 octobre 2016

    HGF: Tiene capacidad mitogénica sobre los hepatocitos y la mayor parte de las células epiteliales.[1] HGF tiene capacidad morfogenética durante el desarrollo embrionario, promueve la migración celular y mejora la supervivencia de los hepatocitos. Se produce...

  • Rejuvenecimiento part VI

    06 octobre 2016

    GDF11: Growth differentiation factor 11, also known as bone morphogenetic protein 11 (BMP-11) is a protein that in humans is encoded by the GDF11 gene.[1] This BMP group of proteins is characterized by a polybasic proteolytic processing site, which is...

  • The Emerging Role of the Insulin-Like Growth Factor Pathway as a Therapeutic Target in Cancer 1. Paula D. Ryan and 2. Paul E. Goss

    06 novembre 2016

    Abstract The insulin-like growth factor signaling pathway is important in many human cancers based on data from experimental models as well as epidemiological studies. Important therapies targeted at this pathway have been or are being developed, including...

  • Alzheimer

    21 novembre 2016

    Alzheimer disease (AD) is a progressive neurodegenerative disorder caused by an increase in amyloid metabolism. Mutations in some of the components of the amyloid pathway, such as the amyloid precursor protein ( APP ), ApoE , Presenilin-1 and PS2 ( PS1...

  • Alzheimer

    21 novembre 2016

    Alzheimer disease (AD) is a progressive neurodegenerative disorder caused by an increase in amyloid metabolism. Mutations in some of the components of the amyloid pathway, such as the amyloid precursor protein ( APP ), ApoE , Presenilin-1 and PS2 ( PS1...

  • Tau-Tubulin Kinase 2

    21 novembre 2016

    Tau -Tubulin Kinase 2 Thi s gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in this gene cause spinocerebellar ataxia type 11 (SCA11); a neurodegenerative disease characterized by progressive ataxia...

  • ASPIRINA (Acido acetil salicilico), factores de resistencia a la aspirina 3

    01 décembre 2016

    Reactividad plaquetaria aumentada: En las condiciones como artritis, valvulas cardíacas, enfermedad cardiaca reumática, endocarditis infecciosa, algunas enfermedades autoinmunes, están asociadas con la presentación persistente de eventos aterotrombóticos...

  • Aptámeros (Anticuerpos químicos)

    02 décembre 2016

    Los aptámeros son oligonucleótidos de cadena sencilla con tamaños entre 70 y 100 nucleótidos capaces de reconocer de forma específica y con alta afinidad a varios tipos de moléculas diana mediante un plegamiento tridimensional de su cadena. Generalmente...

  • First results from young blood Alzheimer’s trial are criticised

    02 novembre 2017

    The long-awaited results of a trial involving the injection of blood from young people as a treatment for Alzheimer’s disease have been met with criticism. In 2014, a team led by Tony Wyss-Coray at Stanford University received approval to inject young...

  • BECAUSE THE BLOOD AND PLASMA OF YOUNG DONORS ACTIVATE GENES THAT INDUCE THE CELLULAR REPROGRAMMATION? "SECOND PART"

    06 juin 2018

    The cell can modify the sensitivity of the receptor, for example by phosphorylation, also by varying the number of receptors that can modify the total signaling strength inside the cell. Nuclear or cytoplasmic receptors are soluble proteins located in...

  • BECAUSE THE BLOOD AND PLASMA OF YOUNG DONORS ACTIVATE GENES THAT INDUCE THE CELLULAR REPROGRAMMATION? "THIRD PART"

    08 juin 2018

    BECAUSE THE BLOOD AND PLASMA OF YOUNG DONORS ACTIVATE GENES THAT INDUCE THE CELLULAR REPROGRAMMATION? "THIRD PART" Rodolfo Sixto Negri (1) Nuclear receptors that are activated by hormones or other proteins activate specific DNA receptors called hormone-sensitive...

  • Second part. Molecular mechanisms and signaling pathways that are activated with blood or plasma from young donors

    19 août 2018

    Akt inhibits apoptosis by phosphorylating the BADcomponent of the BAD/BclXL complex. Phosphorylated BAD binds to 14-3-3 causing dissociation of the BAD/BclXLcomplex and allowing cell survival. Akt activates IKK, which ultimately leads to NF-KappaB activation...

  • ASPIRINE

    30 juin 2018

    The next time you reach for a bottle of Aspirin to treat that headache, you might also be lowering your cancer risk, according to a series of U.K. studies published Tuesday. The three articles -- two published in the Lancet and the other in Lancet Oncology...

  • Ellagic Acid Potentiates the Effect of Quercetin on p21waf1/cip1, p53, and MAP-Kinases without Affecting Intracellular Generation of Reactive Oxygen Species In Vitro1,2

    30 juin 2018

    Susanne U. Mertens-Talcott , Joshua A. Bomser * , Carlos Romero † , Stephen T. Talcott , and Susan S. Percival 3 + Author Affiliations 1. Department of Food Science and Human Nutrition, Institute of Food and Agricultural Sciences, University of Florida,...

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